Senior Quality Bioinformatics Engineer
Quality Assurance
North America
Posted on Aug 20, 2026
The opportunity
We're building AI that can reason over one of the most complex datasets in existence: the human genome. Millions of people trust Sequencing to help them understand their DNA, which means every variant call, every pipeline output, and every genetic insight we deliver has to be right. As a Senior Quality Bioinformatics Engineer, you'll be the last line of defense between our genomic analysis pipelines and the people who depend on them. You'll combine large-scale data analysis with rigorous test automation to make sure the science stays accurate as our platform scales. This is an opportunity to apply deep bioinformatics expertise to build the quality systems that keep genetic insight trustworthy, for a platform that's reshaping how people understand their own health.
Who You Are
We're building AI that can reason over one of the most complex datasets in existence: the human genome. Millions of people trust Sequencing to help them understand their DNA, which means every variant call, every pipeline output, and every genetic insight we deliver has to be right. As a Senior Quality Bioinformatics Engineer, you'll be the last line of defense between our genomic analysis pipelines and the people who depend on them. You'll combine large-scale data analysis with rigorous test automation to make sure the science stays accurate as our platform scales. This is an opportunity to apply deep bioinformatics expertise to build the quality systems that keep genetic insight trustworthy, for a platform that's reshaping how people understand their own health.
Who You Are
- 5+ years of experience in Bioinformatics, Computational Biology, or a related field.
- Strong programming skills in Python and SQL for genomic data analysis.
- Experience with NGS pipelines, variant classification, and data validation.
- A solid understanding of software testing methodologies and automation tools.
- Experience with bug tracking and Agile tools such as JIRA and Confluence.
- Fluency in English, both written and verbal.
- Experience with cloud platforms (AWS, OCI).
- Knowledge of continuous integration (CI/CD) and automated testing frameworks.
- Develop automated test cases for quality control of new code deployments.
- Write scripts and pipelines to analyze large-scale genomic data and detect errors.
- Work closely with engineers and variant curators to improve workflows and catch issues before they reach production.
- Ensure genetic data accuracy and integrity through quality engineering practices across our analysis pipelines.